The Other Brain: The Scientific and Medical Breakthroughs That Will Heal Our Brains and Revolutionize Our Health

The Other Brain: The Scientific and Medical Breakthroughs That Will Heal Our Brains and Revolutionize Our Health

by R. Douglas Fields Ph.D.
The Other Brain: The Scientific and Medical Breakthroughs That Will Heal Our Brains and Revolutionize Our Health

The Other Brain: The Scientific and Medical Breakthroughs That Will Heal Our Brains and Revolutionize Our Health

by R. Douglas Fields Ph.D.

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Overview

Despite everything that has been written about the brain, a potentially critical part of this vital organ has been overlooked—until now. The Other Brain examines the growing importance of glia, which make up approximately 85 percent of the cells in the brain, and the role they play in how the brain functions, malfunctions, and heals itself.

Long neglected as little more than cerebral packing material, glia (meaning “glue”) are now known to regulate the flow of information between neurons and to repair the brain and spinal cord after injury and stroke. But scientists are also discovering that diseased and damaged glia play a significant role in psychiatric illnesses such as schizophrenia and depression, and in neurodegenerative diseases such as Parkinson’s and Alzheimer’s. Diseased glia cause brain cancer and multiple sclerosis and are linked to infectious diseases such as HIV and prion disease (mad cow disease, for example) and to chronic pain. The more we learn about these cells that make up the “other” brain, the more important they seem to be.

Written by a neuroscientist who is a leader in glial research, The Other Brain gives readers a much more complete understanding of how the brain works and an intriguing look at potentially revolutionary developments in brain science and medicine.

Product Details

ISBN-13: 9780743291422
Publisher: Simon & Schuster
Publication date: 01/11/2011
Pages: 384
Sales rank: 791,521
Product dimensions: 6.40(w) x 9.22(h) x 0.94(d)

About the Author

R. Douglas Fields, Ph. D. is the Chief of the Nervous System Development and Plasticity Section at the National Institute of Child Health and Human Development. He received his B.A. from the University of California, Berkeley, an M.A. degree at San Jose State University, and a Ph.D. degree from the University of California, San Diego, working jointly in the Medical School and Scripps Institution of Oceanography.

Fields has conducted postdoctoral research at Stanford University, Yale University, and the NIH. He became Head of the Neurocytology and Physiology Unit, NICHD in 1994, and Chief of the Nervous System Development and Plasticity Section, NICHD in 2001. He is Editor-in-Chief of the journal Neuron Glia Biology, and member of the editorial board of several other journals in the field of neuroscience. He lives in Silver Spring, Maryland.

Table of Contents

Preface VII

Acknowledgments IX

Part I Discovering the Other Brain

Chapter 1 Bubble Wrap or Brilliant Glue? 3

Chapter 2 A Look Inside the Brain: The Cellular Components of the Brain 16

Chapter 3 Transmissions from the Other Brain: Glia Know and Control Your Mind 48

Part II Glia in Health and Disease

Mending the Mind: Glia Repairing Nervous System Damage and Disease 65

Chapter 4 Brain Cancer: Almost Nothing to Do with Neurons 69

Chapter 5 Brain and Spinal Cord Injury 80

Chapter 6 Infection 107

Chapter 7 Mental Health: Glia, Silent Partners in Mental Illness 133

Chapter 8 Neurodegenerative Disorders 162

Chapter 9 Glia and Pain: A Blessing and a Curse 183

Chapter 10 Glia and Addiction: A Neuron-Glia Dependence 200

Chapter 11 Mother and Child 209

Chapter 12 Aging: Glia Rage against the Dying Light 233

Part III Glia in Thought and Memory

Chapter 13 The Mind of the Other Brain: Glia Controlling the Conscious and Unconscious Mind 249

Chapter 14 Memory and Brain Power beyond Neurons 268

Chapter 15 Thinking beyond Synapses 280

Chapter 16 Into the Future: The New Brain 305

Glossary 311

Notes 323

Bibliography 329

Index 359

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